•Clots in ~ blood vessels have the right to obstruct blood flow and cause blockages in organs•Types: venous thromboembolism, pulmonary embolism, coronary thrombosis•Treatment contains a mix of medical and surgical procedures, and also medications•Involves cardiovascular medicine, interventional cardiology


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Blood clots space usually harmless. They type whenever we reduced or scrape our skin or bump into something and also get a bruise. However, when blood clots form within blood ship they have the right to obstruct blood flow, a condition called thrombosis. That can mean trouble. If a clot in one artery breaks totally free and travels with the circulatory system, it can reason blockages affecting the heart, lungs, and other organs—potentially shutting them down.

The results can be deadly. Thrombosis affects up to 900,000 civilization in the United says per year and also kills approximately 100,000.

“At Yale Medicine, patients v suspected thrombosis acquire evaluated an extremely quickly,” claims Michael Remetz, MD, a Yale medication interventional cardiologist. For blood clots that impact the heart: “That is valuable time once the love is being damaged. If a big part that the heart is affected, irreversible heart damage results, or it deserve to be fatal.”


There room three types—venous thromboembolism, pulmonary embolism, and coronary thrombosis. Venous thromboembolism occurs in veins or arteries, most frequently in the legs. Once a blood gerean travels come the lungs and also causes a blockage of one artery, it’s referred to as a pulmonary embolism. Coronary thrombosis is a blockage of one artery in the heart, which can lead come a love attack.


Normal blood clots take place whenever yes an injury to the cells lining blood vessels. However, abnormal blood clots can form if there are unusual sport in blood flow, such together those resulted in by conditions including valvulitis and also aneurysm, or since of conditions that reason blood to clot unnecessarily, such as leukemia or aspect V mutation.

Coronary thrombosis can happen when arteries come to be clogged with cholesterol and fat, making it daunting for blood to circulation through.

Additional risk components for blood coagulation include:

obesity pregnant sitting for prolonged periods of time cigarette smoking dental contraceptives Injury or surgical treatment period (increased threat for world over period 60) A family history of blood clots Chronic inflammatory conditions

Symptoms that thrombosis in veins (which usually influence the legs) include: swelling, pain,, and also cramping.

Symptoms of pulmonary embolism (a blood clot that has actually traveled into the lungs) incorporate shortness the breath, chest pain, and also coughing.

Symptoms of coronary thrombosis (a blood clot that forms in the heart) include severe pains in the chest and also arm, sweating and also trouble breathing.




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The blood clots deserve to be treated with a mix of medical and surgical procedures. The very first line of defense is blood-thinning medications, such together warfarin, which have the right to prevent brand-new clots from creating while the body functions to break up present clots. Aspirin, a blood thinner, is additionally used. A course of medications referred to as thrombolytics deserve to dissolve coagulation even more quickly, yet can boost the danger of bleeding.

Doctors may additionally opt to do surgery to remove the blood clot.


At Yale Medicine, our cardiology team is made up of leading researchers in the field. They command clinical trials for medicines that could not however be accessible on the market and use their knowledge to better diagnose and treat blood clots.

In addition, because that blood clots affecting the heart, ours cardiologists work closely with the emergency departments of area hospitals to treat patients as quickly as possible. They sirloin patients to our catheterization lab one of two people by ambulance or helicopter, whereby our professional clinicians carry out diagnostic procedures, such as state-of-the arts blood tests and also cardiac catheterization. The latter is a procedure whereby a catheter is threaded right into the impacted veins and arteries to clean them.

“The very first two hrs of a heart trouble is when there is most damage to the heart,” says Dr. Remetz.