In our recent question and answer, our pharmacist discusses even if it is or not it yes to take it Zyrtec (cetirizine) with Mucinex.

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Jay asked

This afternoon roughly 4pm ns took a Zyrtec for allergy associated symptoms, 6 hrs I took Mucinex rapid max to aid with runny nose and sneezing. I found out the both have antihistamine in them and I am concerned about if ns took as well much. Both have 10mg the antihistamine in them. Need to I it is in worried?


You don"t must be worried. If you take it Zyrtec and also Mucinex Fast-Max sixhours apart, the worst girlfriend are likely to suffer is included drowsiness and drymouth. Making use of alcohol or various other drugs v either or both of these medicationswill likely intensify the drowsiness considerably. This may significantly impair yourability to journey or usage machinery, so please usage caution and also be safe.

Mucinex Fast-Max is a product heat in which there room multiple execution intended to treat a variety of symptoms. Reviewing the ingredient of every the Fast-Max heat ofproducts, the nighttime arrays contain either diphenhydramine or doxylamineas an antihistamine.

A quick lesson on antihistamines. There are two main families ofantihistamines, let’s call them old-school and also new-school to make it much easier toremember.

Old-school antihistamines include drugs choose

Diphenhydramine (Benedryl)Doxylamine(Unisom, NyQuil)Chlorpheniramine(Chlor-Trimeton, Chlor-Tabs)

These medicine block histamine receptors in both thebrain and the rest of the body; they also interact v several various other receptortypes. This renders them an excellent at relieving allergy symptoms, but additionally gives them afew unpleasant side effects, an especially sedation/drowsiness, dried mouth, anddry eyes.

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New-school antihistamines incorporate drugs like:

Cetirizine (Zyrtec)Fexofenadine (Allegra)Loratadine (Claritin)

These drugs, uneven the old-school ones, are designed so that they can’tcross the obstacle that protects the brain from harmful chemistry in your blood.The result is they have the right to only block histamine receptors uncovered in the rest of yourbody, and not in the brain, and also so they create allergy relief with much lessdrowsiness and other side effects.

That said, this doesn’t typical they can’tmake you drowsy, and taking lock with various other antihistamines, alcohol, or drugsthat impact the main nervous mechanism (bupropion, benzodiazepines likealprazolam or clonazepam, and others) have the right to produce substantial additive effectsthat can impair your capacity to do decisions or operate a vehicle.

Again, mixingthese substances should be avoided if possible, and if you must, use caution.Thanks for your question!