Sulfonamide antibiotics can reason allergic reaction that selection from a soft rash come a severe blistering rash, v to anaphylaxis, i beg your pardon is the many severe form of reaction.

You are watching: Is morphine sulfate a sulfa drug

This paper uses spelling follow to the Australian Therapeutic Goods management (TGA) approved terminology for medicines (1999) in i beg your pardon the terms sulfur, sulfite, sulfate, and also sulfonamide replace sulphur, sulphite, sulphate and sulphonamide.

Sulfonamide antibiotic

A person that is to one sulfonamide antibiotic, is at threat of reacting to other sulfonamide antibiotics. Sulfonamide antibiotics that are easily accessible on prescription in Australia include:

Sulfamethoxazolethat is supplied in mix with trimethoprim.Less commonly used sulfonamide antibiotics together assulfadiazine (tablets, injections or creams), sulfadoxine (for malaria), and sulfacetamide antibiotic eye drops.Sulfasalazine (Salazopyrin, Pyralin), that is supplied in inflammation bowel condition or arthritis, and is a mix sulfapyridine (a sulfonamide antibiotic) and a salicylate.

If a human has had an reaction to Bactrim, Resprim or Septrin, there is no means of knowing whether the was to sulfamethoxazole or to trimethoprim. Thus trimethoprim (Alprim, Triprim) and also sulfonamide antibiotics have to both be avoided.

Sometimes people who have had actually an reaction to a sulfonamide antibiotic are labelled as "sulfur allergic" or to sulfur, sulphur or sulfa. This wording must not it is in used because it is unclear and also can cause confusion. Some human being wrongly assume the they will certainly be allergic to non-antibiotic sulfonamides or to various other sulfur containing medications or sulfite preservatives.

Sulfur is an facet which occurs throughout the human being body as a building block that life, and it is not possible to be allergic to sulfur itself. Allergic reactions to sulfonamide antibiotics do not increase the likelihood of to sulfur powder, sulfite preservatives, sulfates (in medicines, or soaps and shampoos) or non-antibiotic sulfonamide drugs like some pain killers or liquid tablets.

Other varieties of sulfur comprise substances

Elemental sulfur powderis commonly used in gardening, and also while wake up may happen from skin call or inhalation, has not to be described.

Sulfates are in some injectable drugs as sulfate compounds, such together heparin sulfate, dextran sulfate, morphine sulfate. The sulfates in soaps (such as sodium lauryl sulfate) are strong detergents and can wake up the skin or eyes. But sulfate chin does not reason allergic reactions. The is usually safe to usage a sulfate once a person has a sulfonamide or a sulfite intolerance.

Sulfite preventive are generally known together sulfur dioxide and metabisulfites, v preservative numbers 220-228. Sulfites deserve to be supplied to keep flavour and colour within food, inhibit bacterial growth, stop fresh food indigenous spoiling, and assist preserve medication. Sulfites are many often found in wine, dried fruit, and also dried vegetables. Sometimes they are provided in sausages and salads. Lock can additionally occur normally in short concentrations. Sulfites can cause adverse reaction which are like yet do no involve the immune system and also are because of this called intolerances. The most usual reactions room asthma symptoms (in people with underlying asthma) and also rhinitis (hay fever-like) reactions. Sometimes urticaria (hives) might occur, and very rarely, anaphylaxis (severe reaction).

There is no relationship between sulfite sensitivity and sulfonamide antibiotic

Non-antibiotic sulfonamide medicinessuch as some fluid medicines, diabetes medicines and also arthritis medications contain sulfonamide components however these are not sufficiently comparable to sulfonamide antibiotics come pose an risk. These drugs do not should be avoided by world who are allergic come sulfonamide antibiotics due to the fact that the rarely cross-reacts.

Confirming the diagnosis

There is no blood test accessible for to sulfonamide antibiotics, and skin trial and error has no been validated. Skin experimentation has been supplied to check for trimethoprim (to differentiate from sulfamethoxazole in world who have reacted come Bactrim) yet results must be interpreted with caution. An obstacle testing might be carried out under supervision that a clinical immunology and specialist.


People that have had actually an reaction to one sulfonamide antibiotic room usually advised to protect against all sulfonamide antibiotics. As these antibiotics room not normally used in one emergency, wearing medical identification is not routinely recommended return it might be recipient in human being who have had actually anaphylaxis.

Sulfonamide antibiotic is not always lifelong and also cross-reaction walk not constantly occur. Desensitisation to switch turn off temporarily, is obtainable if a sulfonamide antibiotic is the only suitable drug come use.

ASCIA is the peak expert body that clinical immunology/ specialists in Australia and new Zealand.

See more: Pokemon Omega Ruby & Alpha Sapphire: How To Get Groudon In Ruby

ASCIA sources are based upon published literature and also expert review, however, they room not intended come replace medical advice. The contents of ASCIA resources is not influenced by any kind of commercial snucongo.organisations.

For more information go to

To donate come and immunology research go to